Yes, it's possible. Here you can see something similar but showing one week per column. You can switch to one day per column by modifying CellDuration property to 1440 (one day has 1440 minutes).

http://www.daypilot.org/demo/Scheduler/Year.aspx

You can also hide weekends by using ShowNonBusiness=true. In the BeforeTimeHeaderRender you can show/hide individual columns:

protected void DayPilotScheduler1_BeforeTimeHeaderRender(object sender,
    DayPilot.Web.Ui.Events.BeforeTimeHeaderRenderEventArgs e)
{
   if (!e.IsColGroup) {  // visibility can't be set for column groups
     if (e.Start.DayOfWeek == DayOfWeek.Saturday || e.Start.DayOfWeek == DayOfWeek.Sunday)
     {
       e.Visible = false;
     }
   }
}

See also:

• http://blog.daypilot.org/2009/07/scheduler-hiding-non-business-hours.html