yes it only gives the problem when update. i have binded the values in following manner
Server side code on checkBox click
protected void chkClinicList_SelectedIndexChanged(object sender, EventArgs e)
{
DayPilotCalendar1.DataSource = fnGetRecordsBasedOnCritria(strDoctorId, strClinicListId);
DayPilotCalendar1.DataBind();
DayPilotCalendar2.DataSource = fnGetWaitingRecordsBasedOnCritria(strDoctorId, strClinicListId);
DayPilotCalendar2.DataBind();
UpdatePanel1.Update();
UpdatePanel2.Update();
}